Statin efficacy in primary CVD prevention might diminish with patient age
نویسندگان
چکیده
منابع مشابه
Primary prevention of CVD: diet.
INTRODUCTION Diet is important in the cause of many chronic diseases. Individual change in dietary behaviour has the potential to decrease the burden of chronic disease, particularly cardiovascular disease (CVD). METHODS AND OUTCOMES We conducted a systematic review and aimed to answer the following clinical question: What are the effects of dietary advice in generally healthy adults without ...
متن کاملPrimary prevention of CVD: treating dyslipidaemia.
INTRODUCTION The incidence of dyslipidaemia is high: in 2000, approximately 25% of adults in the USA had total cholesterol greater than 6.2 mmol/L or were taking lipid-lowering medication. Primary prevention in this context is defined as long-term management of people at increased risk but with no clinically overt evidence of CVD - such as acute MI, angina, stroke, and PVD - and who have not un...
متن کاملCost-effectiveness of statin therapy for primary prevention in a low-cost statin era.
BACKGROUND With wide availability of low-cost generics, primary prevention with statins has become less expensive. We projected the cost-effectiveness of expanded statin prescribing strategies using low-cost generics and identified conditions under which aggressive prescribing ceases to be cost-effective. METHODS AND RESULTS We simulated expanded statin prescribing strategies with the coronar...
متن کاملStatin therapy for primary prevention of cardiovascular disease.
CLINICAL QUESTION Do statins reduce rates of cardiovascular events when used for primary prevention? BOTTOM LINE When used for primary prevention, statins are associated with lower rates of all-cause mortality, major vascular events, and revascularizations compared with placebo. Statin therapy is not associated with increased rates of life-threatening adverse effects such as cancer.
متن کاملStatin for the Primary Prevention of Cardiovascular Disease in Patients with Diabetes Mellitus
Corresponding author: Bo Kyung Koo Department of Internal Medicine, Boramae Medical Center, Seoul National University College of Medicine, 20 Boramae-ro 5-gil, Dongjak-gu, Seoul 156-707, Korea E-mail: [email protected] Stain is commonly used in subjects with diabetes for both primary and secondary prevention of cardiovascular diseases (CVDs) [1,2]. It is even recommended by the American Di...
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ژورنال
عنوان ژورنال: Nature Reviews Cardiology
سال: 2019
ISSN: 1759-5002,1759-5010
DOI: 10.1038/s41569-019-0171-8